Malegra DXT Plus is a medication that combines two active ingredients: Sildenafil and Duloxetine. Sildenafil, a well-known drug, is the same ingredient found in Viagra, which is used to treat erectile dysfunction. Sildenafil works by increasing blood flow to the penis, allowing for an erection when sexually stimulated. Duloxetine, on the other hand, is typically used to treat depression and anxiety but is also effective in delaying ejaculation, making it helpful for those with both ED and premature ejaculation.