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SIRPα immune checkpoint

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Signal regulatory proteins (SIRP) are a multigene family of immunoreceptors encoded in humans by a cluster of genes on chromosome 20p13. The family encompasses five members with variable levels of amino acid sequence homology, including SIRPα, SIRPβ1, SIRPγ, SIRPβ2, and SIRPδ. The glycoprotein SIRPα, also known as CD172a, SHPS-1, BIT (rat homolog), p84 (mouse homolog), MFR, MYD-1, or PTPNS1, is the primordial and also the best-conserved member of the family. SIRPα immune checkpoint https://immune-checkpoint.crea....tive-biolabs.com/sir

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